2019 •
Driving tau into phase-separated liquid droplets
Authors: Martin Margittai
Venue: Journal of Biological Chemistry
Type: Publication
Abstract: Liquid–liquid phase separation of tau protein has been implicated in normal biological function as well as neurodegenerative diseases, including Alzheimer's. However, knowledge about these links is still scant, and the mechanisms driving tau into liquid droplets are poorly understood. A simplified in vitro system that uses unmodified human tau protein now suggests electrostatic interactions provide the basic instructions underlying liquid droplet formation.
Popularity: This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the
underlying citation network.
Influence: This indicator reflects the overall/total impact of an article in the research community at large, based on the
underlying citation network (diachronically).
Citation Count: This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in
the research community at large, based on the underlying citation network (diachronically).
Impulse: This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation
network.
We have placed cookies on your device to help make this website and the services we offer better. By using this site, you agree to the use of cookies. Learn more