Abstract: At a late stage of spermatogenesis in rainbow-trout testis, the entire complement of histones is replaced by newly synthesized protamine and histones are extensively phosphorylated and acetylated. Tryptic digestion of purified histones labeled by incubation of testicular cells with [ 32 P]phosphate shows that phosphorylation occurs at a small number of seryl residues. Histone I (lysine-rich) is phosphorylated in the sequence Lys-Ser(PO 4 )-Pro-Lys, which is located in the lysine-rich C-terminal region of the molecule. Histones IIb 1 (slightly l...
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Topics: 
Biochemistry
Molecular biology