Abstract: Positron-emission tomography and functional MRS imaging signals can be analyzed to derive neurophysiological values of cerebral blood flow or volume and cerebral metabolic consumption rates of glucose (CMR Glc ) or oxygen (CMR O 2 ). Under basal physiological conditions in the adult mammalian brain, glucose oxidation is nearly complete so that the oxygen-to-glucose index (OGI), given by the ratio of CMR O 2 /CMR Glc , is close to the stoichiometric value of 6. However, a survey of functional imaging data suggests that the OGI is activity depend...
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Topics: 
Internal medicine
Endocrinology
Biochemistry