Authors: Timothy J, Whelan, Jean-Philippe, Pignol, Mark N, Levine, Jim A, Julian, Robert, MacKenzie, Sameer, Parpia, Wendy, Shelley, Laval, Grimard, Julie, Bowen, Himu, Lukka, Francisco, Perera, Anthony, Fyles, Ken, Schneider, Sunil, Gulavita, Carolyn, Freeman
Venue: New England Journal of Medicine
Type: Publication
Abstract: The optimal fractionation schedule for whole-breast irradiation after breast-conserving surgery is unknown.We conducted a study to determine whether a hypofractionated 3-week schedule of whole-breast irradiation is as effective as a 5-week schedule. Women with invasive breast cancer who had undergone breast-conserving surgery and in whom resection margins were clear and axillary lymph nodes were negative were randomly assigned to receive whole-breast irradiation either at a standard dose of 50.0 Gy in 25 fractions over a period of 35 days (the ...
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Topics: 
Surgery
Nuclear medicine
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