Authors: Khadangi, Fatemeh, Forgues, Anne-Sophie, Tremblay-Pitre, Sophie, Dufour-Mailhot, Alexis, Henry, Cyndi, Boucher, Magali, Beaulieu, Marie-Josée, Morissette, Mathieu, Fereydoonzad, Liah, Brunet, David, Robichaud, Annette, Bossé, Ynuk
Venue: Scientific Reports
Type: Publication
Abstract: AbstractDue to frequent and often severe lung affections caused by COVID-19, murine models of acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung research. The one induced by a single lipopolysaccharide (LPS) exposure is practical. However, whether it is preferable to administer LPS intranasally or intratracheally remains an open question. Herein, female C57Bl/6 J mice were exposed intranasally or intratracheally to one dose of either saline or 3 mg/kg of LPS. They were studied 24 h later. The groups treated wi...
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Topics: 
Immunology
Pathology
Pharmacology
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