Authors: Rubino T, Vigano' D, Realini N, Guidali C, Braida D, Capurro V, Castiglioni C, Cherubino F, ROMUALDI, PATRIZIA, CANDELETTI, SANZIO, Sala M, Parolaro D.

Venue: Neuropsychopharmacology

Type: Publication

Abstract: Few and often contradictory reports exist on the long-term neurobiological consequences of cannabinoid consumption in adolescents. The endocannabinoid system plays an important role during the different stages of brain development as cannabinoids influence the release and action of different neurotransmitters and promote neurogenesis. This study tested whether long-lasting interference by cannabinoids with the developing endogenous cannabinoid system during adolescence caused persistent behavioral alterations in adult rats. Adolescent female an... (read more)

DOI: 10.1038/sj.npp.1301664