Abstract: AbstractDeficiencies in the early ADMET (absorption, distribution, metabolism, elimination, and toxicity) information on drug candidates extract a significant economic penalty on pharmaceutical firms. We have developed a microscale cell culture analog (μCCA) device that can potentially provide better, faster, and more efficient prediction of human and animal responses to a wide range of chemicals. The system described in this paper is a simple four‐chamber μCCA (“lung”–“liver”–“fat”–“other tissue”) designed on the basi...
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Topics: 
Pharmacology
Biochemistry