Authors: Brunt, A. Murray, Wheatley, Duncan, Yarnold, John, Somaiah, Navita, Kelly, Stephen, Harnett, Adrian, Coles, Charlotte, Goodman, Andrew, Bahl, Amit, Churn, Mark, Zotova, Rada, Sydenham, Griffin, Clare L, Morden, James P, Bliss, Judith M
Venue: Radiotherapy and Oncology
Type: Publication
Abstract: Background and purposeFAST-Forward is a phase 3 clinical trial testing a 1-week course of whole breast radiotherapy against the UK standard 3-week regimen after primary surgery for early breast cancer. Two acute skin toxicity substudies were undertaken to test the safety of the test schedules with respect to early skin reactions.Material and methodsPatients were randomly allocated to 40 Gy/15 fractions (F)/3-weeks, 27 Gy/5F/1-week or 26 Gy/5F/1-week. Acute breast skin reactions were graded using RTOG (first substudy) and CTCAE criteria v4.03 (s...
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Topics: 
Nuclear medicine
Surgery
Internal medicine
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