Abstract: Abstract CART (cocaine- and amphetamine-regulated transcript) peptides are neuropeptides abundant in the central nervous system and periphery found to be involved in the regulation of food intake behavior and other physiological processes. Recently, we reported specific binding of 125 I-CART(61–102) to the rat adrenal pheochromocytoma cell line PC12, both intact cells and cell membranes. In this study, several fragments of CART(61–102) corresponding to its structural loops were synthesized and tested for their potency in binding experiments...
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Topics: 
Endocrinology
Internal medicine
Biochemistry