Abstract: 1. The replacement of chlorine by ammonia in anilides of α-alkylthio-β-chloroisovaleric acid in nitromethane, methanol, and water takes place with the formation of an episulfonium ion and results in the formation of anilides of S-alkyl-β,β-dimethylcysteine and isodimethylcysteine. 2. Methyl α-alkylthio-β-chloroisovalerates react with liquid NH3 and its solutions methanol and nitromethane according to a mechanism involving the splitting off of HCl and the addition of NH3. 3. The rate of the splitting off of HCl depends on the nature of the...
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Topics: 
Combinatorial chemistry
Organic chemistry