Abstract: Heat shock proteins have been detected in many mammalian tissues, including the nervous system. In recent years, the family of small molecular weight heat shock proteins, Hsp27, Hsp32 (heme oxygenase), and αB-crystallin, have been shown to be similarly expressed and regulated in response to a variety of challenges. While Hsp27 has been detected in several organs in mammals (Klemenz et al. 1993; Tanguay et al. 1993), its expression and distribution in the central nervous system are particularly striking in both development and in the adult, nor...
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Topics: 
Neuroscience