Abstract: Development of an organism is accompanied by rapid and complex changes within a relatively short period, and embryotoxic chemicals administered to a mother during pregnancy can result in persistent lesions, general growth retardation, or delayed organ growth. In vitro toxicity tests are useful for evaluating the safety or hazards of small quantities of chemicals. Since cell death and inhibition of differentiation in mouse embryonic stem cells (ESCs) can occur within different concentration ranges of compounds, depending on the toxic potency of ...
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Topics: 
Toxicology
Pharmacology