Abstract: During the last years significant progress has been made in the development and validation of animal-free methods for assessing skin sensitization. Despite these advances, more efforts are still needed to refine the existing methods and to further develop new methods that lead to an improved awareness of the real mechanisms of a chemical in triggering a sensitization reaction in exposed human beings. An important observation is that detailed analysis of chemicals producing misleading results may help to define limitations of the respective test...
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Topics: 
Risk analysis (engineering)
Biochemical engineering
Data science