Abstract: Stem cells (SCs) are defined by two major features, self-renewal and pluripotency. Moreover, SCs are classified as embryonic (ESC), adult (ASC), and induced pluripotent (iPSC) stem cells. SCs are capable of differentiation into various types of cells, and have therefore been applied to investigations of genome and cellular functions, genetic therapy, toxicity, and drug screening. Drug screening using stem cells is useful for investigating developmental toxicity, tissue specificity, and disease-specific responses. The embryonic stem cell test (E...
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Topics: 
Pharmacology