Abstract: AbstractThis paper reviews the current status of structure‐based methods for predicting adverse reproductive effects in mammals. The methods described include (Quantitative) Structure–Activity Relationships ((Q)SARs), expert systems and the less formalised approaches of read‐across within (chemical) categories. There are a number of problems with applying QSARs to reproductive toxicology notably the complexity, subtlety and sometimes ill‐defined nature of the endpoints and lack of data available for modelling. A small number of ((Q)SARs...
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Topics: 
Computational biology
Toxicology
Risk analysis (engineering)