Abstract: In areas of inter-laboratory quality control, method comparisons, assay validation and individual bioequivalence, etc., the agreement between observations and target (reference) values is of interest. The mean of the squared difference between observations and target values (MSD) is a good measure of the total deviation. A new user-friendly statistic, the total deviation index (TDI1-p), is introduced that translates the MSD into an index that can be directly compared to a predetermined criterion. The TDI1-p describes a boundary such that a majo...
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